个人简历

2006年09月–2010年06月，安徽大学，化学化工学院，化学专业，获理学学士学位；

2010年09月–2013年06月，安徽大学，化学化工学院，有机化学专业，获理学硕士学位，导师：周虹屏教授；

2013年09月–2016年09月，法国里昂高等师范，化学专业，获博士学位，导师：Chantal Andraud教授；

2016年11月–2020年06月，香港科技大学，化学系，博士后，合作导师：唐本忠教授；

2020年07月–至今，合肥工业大学，9778818威尼斯，黄山青年学者，研究员。

主要研究领域、方向

硕士生招生专业：化学（学术型）；化学工程（专业型）

主要研究方向：新型有机发光材料的设计开发、机理研究及探索其在生物医学、刺激响应材料、光电器件等领域方面的应用。

主讲本科生课程：《有机化学C》《有机结构理论》《基础化学》

研究成果（代表性成果）

迄今已在国际重要学术期刊上发表SCI学术论文四十余篇，以第一作者（包括共一）和通讯作者发表论文二十余篇，包括Adv. Mater.、ACS Nano、Adv. Funct. Mater.、Nano Today、Mater. Horiz.、Chem. Sci.、Biomaterials、Appl. Mater. Interfaces等。其中14篇论文影响因子大于10，3篇论文入选ESI高被引。部分研究成果被ACS Noteworthy Chemistry、MaterialsViews China等国内外知名学术媒体作为亮点报道。入选2022年安徽省级人才计划（青年项目）。多次受邀在国际/国内学术会议上作邀请报告。

目前承担科研项目

（1）国家自然科学基金青年项目（22105057），2022.01-2024.12，主持；

（2）安徽省留学回国人员创新创业计划（2022LCX022），2022.11-2023.11，主持；

（3）中央高校基本科研业务费项目（JZ2023HGTB0228），2023.04-2024.12，主持；

（4）无机有机杂化功能材料化学安徽省重点实验室开放课题，2021.01-2022.12，主持；

（5）合肥工业大学“黄山青年学者”引进人才启动基金，2020.07-2023.07，主持。

获奖及专利情况

获奖：

（1）安徽省自然科学三等奖（4/5），2020年；

（2）安徽省第三届普通高等学校大学生化学竞赛“优秀指导教师”；

（3）指导学生参加安徽省第三届普通高等学校大学生化学竞赛获一等奖，第一指导老师；

专利：

（1）郑正，曹辉，苟学鑫，杨天雨，具有聚集诱导发光性质的化合物及其制备方法和应用，中国，ZL202211248006.1，已授权；

（2）唐本忠，郑正，用于单线态氧生成与癌症消融的荧光探针，中国，ZL202080013949.9，已授权；

（3）唐本忠，郑正，具有强双光子吸收的近红外化合物的制备及应用，中国，ZL201910265433.2，已授权。

著作论文（代表作）

[1] Hui Cao#, Ya Gao#, Bingshun Wu, Jianyu Zhang, Lianke Wang, Peifa Wei, Lijie Liu, Hang Zou*, Hongping Zhou, Zheng Zheng*, Ben Zhong Tang*. Tuning Molecular Packing by Twisting Structure to Facilely Construct Highly Efficient Solid-State Fluorophores for Two-Photon Bioimaging and Photodynamic Therapy, Adv. Funct. Mater., 2024, 2315692.

[2] Jing Wang#, Xiaona Fang#, Jiezhen Yang#, Qin Tang, Yuchen Yang, Zeng Li,Feifei Zhang, Qiang Wu*, Zhaofeng Luo*, Zheng Zheng*. Visualization of tumor-associated neutrophils in malignant ascites of ovarian cancer with aptamer-decorated AIE probes, Sens. Actuators B Chem., 2024, 405, 135385.

[3] Zheng Zheng*, Yuchen Yang, Pingping Wang, Xuexin Gou, Junyi Gong, Xiaoqian Wu, Zhiwei Bao, Lijie Liu, Jing Zhang, Hang Zou*, Lei Zheng*, Ben Zhong Tang*. A Bright Two-Photon Lipid Droplets Probe with Viscosity-Enhanced Solvatochromic Emission for Visualizing Lipid Metabolic Disorders in Deep Tissues, Adv. Funct. Mater., 2023, 2303627.

[4] Haoran Wang#, Qiyao Li#, …, Zheng Zheng*, …, Ben Zhong Tang*. Aggregation-Induced Emission (AIE), Life and Health, ACS Nano, 2023, 17, 14347-14405.

[5] Zheng Zheng*, Tianyu Yang, Dongyu Li, Hui Cao, Junyi Gong, Haixiang Liu, Chengcheng Zhou, Lijie Liu, Peifa Wei, Xinggui Gu, Ping Lu, Jun Qian*, Ben Zhong Tang*. Molecular and Aggregate Synergistic Engineering of Aggregation-Induced Emission Luminogens to Manipulate Optical/Electronic Properties for Efficient and Diversified Functions, ACS Nano, 2023, 17, 8782-8795.

[6] Zheng Zheng*#, Hequn Zhang#, Hui Cao, Junyi Gong, Mubin He, Xuexin Gou, Tianyu Yang, Peifa Wei, Jun Qian, Wang Xi*, Ben Zhong Tang*. Intra- and Intermolecular Synergistic Engineering of Aggregation-Induced Emission Luminogens to Boost Three-Photon Absorption for Through-Skull Brain Imaging, ACS Nano, 2022, 16, 6444-6454.

[7] Mubin He#, Dongyu Li#, Zheng Zheng#, Hequn Zhang, Tianxiang Wu, Weihang Geng, Zhengwu Hu, Zhe Feng, Shiyi Peng, Liang Zhu, Wang Xi, Dan Zhu, Ben Zhong Tang*, Jun Qian*. Aggregation-induced emission nanoprobe assisted ultra-deep through- skull three-photon mouse brain imaging, Nano Today, 2022, 45, 101536.

[8] Yanhong Duo*#, Meng Suo#, Daoming Zhu, Zihuang Li*, Zheng Zheng*, Ben Zhong Tang*. AIEgen-Based Bionic Nanozymes for the Interventional Photodynamic Therapy-Based Treatment of Orthotopic Colon Cancer, ACS Appl. Mater. Interfaces, 2022, 14, 26394-26403.

[9] Xinghua Yu, Ying-Chuan Zhang, Xing Yang, Ziyang Huang, Tianfu Zhang, Liusi Yang, Wenjing Meng, Xiaotong Liu, Ping Gong, Alessandra Forni, Zheng Zheng*, Bilu Liu, Pengfei Zhang*, Lintao Cai, Ben Zhong Tang*. Bonsai-inspired AIE nanohybrid photosensitizer based on vermiculite nanosheets for ferroptosis-assisted oxygen self-sufficient photodynamic cancer therapy, Nano Today, 2022, 44, 101477.

[10] Tianfu Zhang#, Jianyu Zhang#, Fu-Bing Wang#, Hui Cao, Daoming Zhu, Xiaoyu Chen, Changhuo Xu, Xueqin Yang, Wenbin Huang, Zhaoyu Wang, Jiefei Wang, Zikai He, Zheng Zheng*, Jacky W. Y. Lam*, Ben Zhong Tang*. Mitochondria-Targeting Phototheranostics by Aggregation-Induced NIR-II Emission Luminogens: Modulating Intramolecular Motion by Electron Acceptor Engineering for Multi-Modal Synergistic Therapy, Adv. Funct. Mater., 2022, 2110526.

[11] Wei He#, Zheng Zheng#, Haotian Bai*, Ling-Hong Xiong, Lei Wang, Yinghui Li, Ryan T. K.Kwok, Jacky W. Y. Lam, Qinghua Hu, Jinquan Cheng*, Ben Zhong Tang*. A Biocompatible Dual-AIEgen System without Spectral Overlap for Quantitation of Microbial Viability and Monitoring of Biofilm Formation. Mater. Horiz., 2021, 8, 1816-1824.

[12] Yanhong Duo#, Daoming Zhu#, Xiurong Sun#, Meng Suo, Zheng Zheng*, Wei Jiang*, Ben Zhong Tang*. Patient-derived microvesicles/AIE luminogen hybrid system for personalized sonodynamic cancer therapy in patient-derived xenograft models, Biomaterials, 2021, 272, 120755.

[13] Tianfu Zhang#, Zhicong Zhou#, Zheng Zheng*, Jianyu Zhang, Ying Yu, Jacky W. Y. Lam, Jonathan E. Halpert*, Ben Zhong Tang*. “Simple” AIEgens for Non‐doped Solution‐Processed OLEDs with Emission Close to Pure Red in sRGB Gamut, Adv. Photonics Res., 2021, 2100004.

[14] Daoming Zhue#, Zheng Zheng#, Guanghong Luo#, Meng Suo, Xianming Li*, Yanhong Duo*, Ben Zhong Tang*. Single injection and multiple treatments: An injectable nanozyme hydrogel as AIEgen reservoir and release controller for efficient tumor therapy, Nano Today, 2021, 37 101091.

[15] Zheng Zheng#, Haixiang Liu#, Shaodong Zhai, Haoke Zhang, Guogang Shan, Ryan T. K. Kwok, Chao Ma, Herman H. Y. Sung, Ian D. Williams, Jacky W. Y. Lam, Kam Sing Wong, Xianglong Hu*, Ben Zhong Tang*. Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens, Chem. Sci., 2020, 11, 2494-2503.

[16] Zheng Zheng#, Dongyu Li#, Zhiyang Liu, Hui-Qing Peng, Herman H. Y. Sung, Ryan T. K. Kwok, Ian D. Williams, Jacky W. Y. Lam, Jun Qian*, Ben Zhong Tang*. Aggregation-Induced Nonlinear Optical Effects of AIEgen Nanocrystals for Ultra-Deep In Vivo Bio-Imaging, Adv. Mater., 2019, 1904799.

[17] Zheng Zheng#, Tianfu Zhang#, Haixiang Liu#, Yuncong Chen, Ryan T. K. Kwok, Chao Ma, Pengfei Zhang, Herman H. Y. Sung, Ian D. Williams, Jacky W. Y. Lam, Kam Sing Wong, Ben Zhong Tang*. Bright Near-Infrared Aggregation-Induced Emission Luminogens with Strong Two-Photon Absorption, Excellent Organelle Specificity, and Efficient Photodynamic Therapy Potential, ACS Nano, 2018, 12, 8145-8159.